#459 Research shows that in some cases placebo doesn't have to be concealed (open-label) to be effective,
i.e. even if the person knows he/she is getting placebo the effect is still there - close to indentical with blinded placebo.
ine whether OLP treatment is superior to no-pill control (NPC) in irritable bowel syndrome (IBS) and, second, to compare the efficacy of OLP against double-blind placebo (DBP). In a 6-week, 3-arm, randomized clinical trial, participants were randomized in equal proportions to 3 arms: OLP, DBP...
journals.lww.com
OLP [open-label placebo] and DPB [sic!] [double-blind placebo] had similar effects that did not differ significantly, suggesting that blinding may not be necessary for placebos to be effective...
#460 The word
silhouette comes from the French minister of finance, Etienne de Silhouette, in the 18th. century.
Because of his austere economic policies (after the Seven Year's War) "his name became synonymous with anything done or made cheaply and so with these outline portraits".
en.wikipedia.org
#461 One of the longest aqueducts in the Roman empire in Tunisia - 132 km. -
was restored in 1862 and still supplies the town of Tunis with water.
(Although it's mainly the ground level channels and modern pressure pipes that are used)
en.wikipedia.org
#462 "The record speed for a British long drop hanging was seven seconds from the executioner entering the cell to the drop."
en.wikipedia.org
#463 In his lecture "
From Versailles to Cybernetics" Bateson argues that the treaty of Versailles and the development of cybernetics are the only two anthropologically important events of the twentieth century.
en.wikipedia.org
#464 While writing his famous
The Harmony of the World - which includes his 3rd law of planetary motion - Johannes Kepler was also defending his mother, Katharina, from accusations of witchcraft (in 1615).
en.wikipedia.org
#465 Among the many practical challenges on establishing a permanent habitat on the Moon is the combination of a light atmosphere and the dust/rocks. When a ship lands the rocks are hurled in all directions like projectiles, potentially shooting asunder any structure/building nearby.
#466 In the 1990s to the 2000s the camorra (Italian mafia) dumped waste in an area since known as the
triangle of death (near Naples).
A 2004 study revealed that deaths by cancer in the area are much higher than the European average.
en.wikipedia.org
#467 El Greco (the painter) once offered to redo the Last Judgement in the Sistine Chapel, painting over the work of Michelangelo (mainly the nudity that had gone out of fashion), saying "the Old Master ‘did not know how to paint". It was very much criticised, and he soon after left Rome (for Spain).
A leading figure of the Spanish Renaissance, El Greco was actually a Cretan native who had trained in Italy. Read on to discover more about this important and influential artist.
www.thecollector.com
#468 Oi is "a type of punk rock featuring violent, racist lyrics, associated especially with skinheads."
The world's leading online dictionary: English definitions, synonyms, word origins, example sentences, word games, and more. A trusted authority for 25+ years!
www.dictionary.com
#469 The popularity of Robinson Crusoe (released in 1719) lead to an entire genre of books known then and now as
Robinsonade.
Not only in the UK but all over Europe, many authors would sell their books with the word
Robinsonade on the cover.
en.wikipedia.org
#470 In 1990 Denmark was the first country in the world to introduce a state-controlled organic label,
and the country has the highest organic market share in the world with 12.8% of food bought in supermarkets and every third carton of milk purchased certified organic.
National event to mark organic dairy cattle’s release from winter barns has been online only since 2020
www.theguardian.com
