I tend to favor a Vampire/Artificer setup, and try to go for Lich eventually, so I can reroll Poe's stat rewrite ability until I get some numbers I like.
I dig the Fleshburner's set. That artifact lance is a consistently awesome weapon that I still use even above level 30 (great for taking out those Shadow Warriors before they can get within reach of me). The armor is also great in the beginning and lightweight enough in case you hop off your horse to berserk as much as I do.
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