Oh, for the love of...
First, we have an anti-ctd thread,
Second, I said it many times and I'll say it again: never play with automatic saves. And there are rules of saving which I and other people mentioned several times here and there but now I added them to the anti-ctd thread too.
Perisno is a biiiiiiiiig mod. It needs time to save (Perisno saves - 15k+ Kbs, PoP saves - 5k+ Kbs, Native saves - 3k+ Kbs). When you're saving hastily, without pausing (and that's how autosaves are made), the risk of corruption is high, even in smaller mods like PoP, let alone in Perisno.
Whatever we do with the mod we can't possibly change the Warband saving/loading algorithm.
Avoiding ctds on saving and corrupted save files is only up to players. Whether by saving properly or by playing Native and equally small modules.