Hi,
i play with the custom Proton build and without dotnet48. I can play, but there are a lot of crashes. Maybe every 3th or 4th time i talk to a NPC it will crash. Reloading game, talk again to the NPC, everything is fine. But with the time waiting for saving and restarting game, maybe i am able to play 30 minutes per hour.
But with dotnet48 it crashes twice the time. And not only by talking to NPCs.